​65D Syringe Pump

High Pressure Applications – up to 20,000 psi (1,379 bar)

The new 65D is our best pump for very high pressures or very low flow rates. A dual-pump 65D system is available with air valves.


Pumps Overview BrochureBrochure
65D High Pressure Syringe Pump DatasheetDatasheet
Flat Panel Controller for D-Series Tech BulletinLegacy Document
D-Series and HLf-Series Syringe Pump Controller VersionsTechnical Bulletin
D-Series Quad Dual Pump Systems for Continuous Flow and Independent Operation Tech BulletinTechnical Bulletin
Wash Glands for D-Series Tech BulletinTechnical Bulletin
D-Series Syringe Pumps User ManualUser Manual


When you purchase instruments from Teledyne ISCO, you not only receive innovative, high quality products, you also receive excellent customer service and product support. Your initial purchase is only the beginning of Teledyne ISCO's ongoing commitment to their customers.


​​​​​​65D Syringe Pump

​Capacity ​68 mL
​Flow Range
0.00001 to 25 mL/min
​Flow Accuracy
​± 0.3% of setpoint
​Displacement Resolution
​2.5 nL/step
​Press Range
10 to 20,000 psi (​0.7 to 1380 bar)
​Standard Pressure Accuracy
​0.5% Full Scale
​Optional Pressure Accuracy
​0.1% Full Scale
​Wetted Materials
​Nitronic 50, PTFE, Hastelloy C-276
​Plumbing Ports
​1/4", F250C
​Operating Temperature
​5 to 40 °C Ambient
​Power Requirements
​100 VAC, 117 VAC, 234 VAC, 50/60 Hz
​Dimensions (H x W x D)
39.8 x 10.7 x 18.4 inch (101 x 27 x 47 cm)
​​Pump - 72.3 lb (32.8 kg)
Controller - 6.5 lb (3.0 kg​)

​For a full list of product specifications, see the datasheet.




Standard Features

  • 65D pump has 1/4" F-250 fittings for secure high-pressure connections.
  • Rugged single-ratio drive train has auto-lubricating gears to assure long life and low maintenance.
  • Each ISCO D-Series syringe pump is bench tested at the factory.
  • Exclusive "Smart Key" controller. All ISCO D-series pumps use the same controller that can operate any four pump modules, either independently or together. Operating modes include:
    • Single pump independent constant flow or pressure
    • Single pump flow - or pressure - ramp programming
    • Single pump dispensing
    • Dual pump continuous constant flow or pressure 
    • Dual pump concentration gradients
    • Four-pump configured systems
  • RS-232/485 serial interface for computer control or monitoring of operating parameters.
  • Redundant safety is designed in. All D-Series pumps have mechanical and electrical fail-safes, in addition to the factory default or user-set limits.
  • Corrosion resistance. Nitronic 50 - the standard material for cylinders, pistons, and caps - is an austenitic stainless steel with outstanding strength and corrosion resistance.
  • Standard seals are heavy-duty, graphite-impregnated Teflon, providing very long life under harsh operating conditions.


  • High-pressure experiments requiring precision control
  • Proteomics research using nanobore capillary packed columns
  • Rock core analyses for hydrocarbon recovery studies in deep-well reservoirs
  • Chemical/reactant feed in chemical process development, catalyst evaluation, plastic formation

Options and Accessories

  • Temperature control jacket (cylinder cooling for filling with liquefied gas; thermal stabilization for ultra-low flow rates)
  • High-precision pressure transducers (0.1% linear accuracy)
  • Drivers for LabVIEW graphical programming software from National Instruments
  • 4-20 mA input for flow rate and pressure control.
  • Extension cable for connecting controller up to 15 meters (50 feet) from the pump.
  • Air valve package for continuous flow.