​500D Syringe Pump

Ideal for a wide range of chemical feed and core flooding applications

The 500D is ideal for a wide range of chemical feed applications requiring flow rates up to 200 mL/min at pressures up to 3,750 psi (259 bar). With its 500 mL cylinder capacity, this pump can deliver a precise 1 mL/minute for over 8 hours on a single fill. For non-stop continuous flow, see dual pump systems with a choice of valve packages.

As with all D-Series pumps, you'll get accurate, predictable flow and pressure control throughout a remarkable operating range. Patented digital position monitoring servo circuitry provides low-flow precision at any pressure, plus the high speed smoothness and power of a DC motor.


Pumps Overview BrochureBrochure
Pumps Pharmaceutical BrochureBrochure
500D High Pressure Syringe Pump DatasheetDatasheet
Mixer Kit DatasheetDatasheet
Flat Panel Controller for D-Series Tech BulletinLegacy Document
D-Series and HLf-Series Syringe Pump Controller VersionsTechnical Bulletin
D-Series Quad Dual Pump Systems for Continuous Flow and Independent Operation Tech BulletinTechnical Bulletin
Wash Glands for D-Series Tech BulletinTechnical Bulletin
D-Series Syringe Pumps User ManualUser Manual


When you purchase instruments from Teledyne ISCO, you not only receive innovative, high quality products, you also receive excellent customer service and product support. Your initial purchase is only the beginning of Teledyne ISCO's ongoing commitment to their customers.


​​​​​500D Syringe Pump

​Capacity ​507 mL
​Flow Range
​0.001 to 204 mL/min
​Flow Accuracy
​0.5% of setpoint
​Displacement Resolution
​31.71 nL
​Pressure Range
10 to 3,750 psi (0.7 to 258.6 bar)
​Standard Pressure Accuracy
​0.5% Full Scale
​Optional Pressure Accuracy
​0.1% Full Scale
​Wetted Materials
​Nitronic 50, PTFE, Hastelloy C-276
​Plumbing Ports
​1/8" NPT
​Operating Temperature
​5 to 40 °C Ambient
​Power Requirements
​100 VAC, 117 VAC, 234 VAC, 50/60 Hz
​Dimensions (H x W x D)
40.3 x 10.7 x 18.4 inch (​102 x 27 x 47 cm)
​Weight ​Pump - 73.3 lb (33.3 kg)
Controller - 6.5 lb (3.0 kg​)

​For a full list of product specifications, see the datasheet.​



Standard Features

  • 500D pump has 1/8" NPT inlet and outlet ports for rapid, low-restriction filling and dispensing and easy connection in process and pilot-plant plumbing.
  • Integral button-style pressure transducer in cylinder cap assures excellent stability and repeatability.
  • Rugged single-ratio drive train has auto-lubricating gears to assure long life and low maintenance.
  • Each ISCO D-Series syringe pump is bench tested at the factory.
  • Exclusive "Smart Key" controller. All ISCO D-series pumps use the same controller that can operate any four pump modules, either independently or together. Operating modes include:
    • Single pump independent constant flow or pressure
    • Single pump flow - or pressure - ramp programming
    • Single pump dispensing
    • Dual pump continuous constant flow or pressure
    • Dual pump concentration gradients 
  • RS-232/485 serial interface for computer control or monitoring of operating parameters.
  • Redundant safety is designed in. All D-Series pumps have mechanical and electrical fail-safes, in addition to the factory default or user-set limits.
  • Corrosion resistance. Nitronic 50 - the standard material for cylinders, pistons, and caps - is an austenitic stainless steel with outstanding strength and corrosion resistance.
  • Standard seals are heavy-duty, graphite-impregnated Teflon, providing very long life under harsh operating conditions.


  • Precision fluid addition in research and manufacturing processes
  • Chemical/reactant feed in chemical process development, catalyst evaluation, plastic formulation
  • Accurate metering of liquefied gases

Options and Accessories

  • Hastelloy construction
  • Temperature control jacket (cylinder cooling for filling with liquefied gas; thermal stabilization for ultra-low flow rates)
  • High-temperature pressure transducers (for operation with pump cylinder heated up to 200 °C maximum)
  • High-precision pressure transducers (0.1% linear accuracy)
  • Drivers for LabVIEW graphical programming software from National Instruments
  • Alternate seals optimized for special applications: virgin Teflon for corrosive fluids, heavy duty reinforced for slurries and viscous fluids, high temperature, low temperature, and UHMW polyethylene. Choice of seals can be ordered factory-installed.
  • Slurry mixer kit