​100DX Syrin​ge Pump

High Pressure Applications - up to 10,000 psi (690 bar)

The 100DX was developed initially to meet the demand for a 10,000 psi (690 bar) pump with fast flow and refill for Supercritical Fluid Extraction. It has also found many other applications for jobs requiring the combination of high pressure and flow rate up to 50 mL/minute. For the ultimate low-flow precision, we recommend the 65DM model, which has the same pressure rating but is geared for maximum flow of 30 mL/minute and triple the displacement resolution of the 100DX.

Dual-pump 100DX systems are available with a choice of valve packages for non-stop continuous flow.


DoC 100DX Hastelloy
DoC 100DX
Pumps Overview BrochureBrochure
100DX High Pressure Syringe Pump DatasheetDatasheet
Flat Panel Controller for D-Series Tech BulletinLegacy Document
D-Series and HL-Series Syringe Pump Controller Versions Tech BulletinTechnical Bulletin
D-Series Quad Dual Pump Systems for Continuous Flow and Independent Operation Tech BulletinNewTechnical Bulletin
Wash Glands for D-Series Tech BulletinTechnical Bulletin
D-Series Syringe Pumps User ManualUser Manual


When you purchase instruments from Teledyne ISCO, you not only receive innovative, high quality products, you also receive excellent customer service and product support. Your initial purchase is only the beginning of Teledyne ISCO's ongoing commitment to their customers.


​​100DX Syringe Pump

​Capacity ​103 mL
​Flow Range
​0.0001 mL/min to 50 mL/min
​Flow Accuracy
​0.3% of setpoint
​Displacement Resolution
​9.6 nL
​Pressure Range
10 to 10,000 psi (0.7 to ​689.5 bar)
​Standard Pressure Accuracy
​0.5% Full Scale
​Optional Pressure Accuracy
​0.1% Full Scale
​Wetted Materials
​Nitronic 50, PTFE, Hastelloy C-276
​Plumbing Ports
​1/8" Valco
​Operating Temperature
​5 to 40 °C Ambient
​Power Requirements
​100 VAC, 117 VAC, 234 VAC, 50/60 Hz
​Dimensions (H x W x D)
39.8 x 10.7 x 18.4 inch (​101 x 27 x 47 cm)
​Weight ​Pump - 72.3 lb (32.8 kg)
Controller - 6.5 lb (3.0 kg​)

​For a full list of product specifications, see the datasheet.



Standard Features

  • 100DX pump has 1/8" Valco fittings for secure high-pressure connections.
  • Integral button-style pressure transducer in cylinder cap assures excellent stability and repeatability.
  • Rugged single-ratio drive train has auto-lubricating gears to assure long life and low maintenance.
  • Each ISCO D-Series syringe pump is bench tested at the factory.
  • Exclusive "Smart Key" controller. All ISCO D-series pumps use the same controller that can operate any four pump modules, either independently or together. Operating modes include:
    • Single pump independent constant flow or pressure
    • Single pump flow - or pressure - ramp programming
    • Single pump dispensing
    • Dual pump continuous constant flow or pressure
    • Dual pump concentration gradients 
    • Four-pump configured systems
  • RS-232/485 serial interface for computer control or monitoring of operating parameters.
  • Redundant safety is designed in. All D-Series pumps have mechanical and electrical fail-safes, in addition to the factory default or user-set limits.
  • Corrosion resistance. Nitronic 50 - the standard material for cylinders, pistons, and caps - is an austenitic stainless steel with outstanding strength and corrosion resistance.
  • Standard seals are heavy-duty, graphite-impregnated Teflon, providing very long life under harsh operating conditions.


  • Supercritical Fluids techniques including extraction, reaction, and chromatography
  • Precision fluid feed in small-scale experiments
  • Rock core flooding experiments in fossil fuel reservoir research and development

Options and Accessories

  • Hastelloy construction
  • Temperature control jacket (cylinder cooling for filling with liquefied gas; thermal stabilization for ultra-low flow rates)
  • High-temperature pressure transducers (for operation with pump cylinder heated up to 200°C maximum)
  • High-precision pressure transducers (0.1% linear accuracy)
  • Drivers for LabVIEW graphical programming software from National Instruments
  • Alternate seals optimized for special applications: virgin Teflon for corrosive fluids, heavy duty reinforced for slurries and viscous fluids, high temperature, low temperature, and UHMW polyethylene. Choice of seals can be ordered factory-installed.