The ACCQPrep® SFC is a compact system that simplifies method complexity and ensures successful separations for users of all experience levels. As the only system to enable both bulk collection from stacked injections, and multi-sample, open-access with an optional SFC AutoSampler (2x2 or 4x2), the ACCQPrep SFC offers versatility without limitations; all in the smallest Prep SFC footprint on the market.
Stacked injections increase throughput by performing additional injections, while compounds from previous injections elute. The PeakTrak® software’s Stacked Injection Wizard intelligently determines cycle time and fraction collection settings, automatically suggests “time windows” for collection of desired peaks, and injection simulation assists the user in visualizing the effect of method modifications.
Because the dynamic nature of supercritical CO2 requires accurate flow control and back pressure regulation, the ACCQPrep SFC has a robust CO2 pumping system paired with an advanced mass-flow controller and automated backpressure regulation. Prior to fraction and waste collection, the patented Gas-Liquid Separator (GLS) minimizes carryover, resists clogging, and permits high cosolvent flow. Finally, a standard fractionation valve sorts collection into up to eight vessels or output to 2x2 or 4x2 SFC AutoSampler for full open-bed
fraction collection with >95% recovery up to 200 mL/min.
The ACCQPrep SFC’s simple PeakTrak software interface is navigated via a high-resolution, integrated 15” touchscreen. Method setup includes gradient, temperature, and backpressure parameters, while the software automatically determines GLS and fraction collection delay settings based on cosolvent composition. Because achieving the most efficient purification is essential, the software’s Focused Gradient Generator creates an optimized gradient profile focused on the elution of the compound of interest. Additional practical software features include solvent level monitoring to prevent ruined separations, waste level sensing to prevent overflows and AutoSampler recognized RFID collection racks to eliminate missed or overfilled test tubes.