CombiFlash NextGen 300CombiFlash NextFen 300

Setting a New Standard in Flash Chromatography Performance


The CombiFlash NextGen 300 is configurable to your needs. The system is designed for liquid injections, operating at up to 160 psi (11 bar). If needed, add the solid load injection valve (increases the operating pressure limit to 300 psi (20bar)) and increase the system's versatility. Similarly, RFID rack and column read and solvent and waste level sense can be added if desired. You determine what your needs are and don't pay for unused or unwanted features.



    CombiFlash NextGen Quick Start Guide.pdfCombiFlash NextGen Quick Start GuideQuick Start Guide
    CombiFlash NextGen User Manual.pdfCombiFlash NextGen User ManualUser Manual
    CombiFlash NextGen Safety Sheet.pdfCombiFlash NextGen Safety SheetInstruction Sheet
    CombiFlash System Verification Instructions.pdfCombiFlash System Verification InstructionsInstruction Sheet
    CombiFlash NextGen 300 Datasheet.pdfCombiFlash NextGen 300 DatasheetDatasheet
    CombiFlash NextGen Brochure.pdfCombiFlash NextGen BrochureBrochure
    CombiFlash Pump Seal Replacement Instructions.pdfCombiFlash Pump Seal Replacement InstructionsInstruction Sheet
    NextGen 300 Pump Greasing Instructions.pdfNextGen 300 Pump Greasing InstructionsInstruction Sheet


    When you purchase instruments from Teledyne ISCO, you not only receive innovative, high quality products, you also receive excellent customer service and product support. Your initial purchase is only the beginning of Teledyne ISCO's ongoing commitment to their customers.


    ​CombiFlash® NextGen 300

    ​Flow Rate Range
    ​1 - 300 mL/min
    ​Pressure Limit

    ​300  psi (20 BAR) with injection valve

    160 psi (11 BAR) without injection valve

    ​Column Sizes
    ​4 - 750 g
    Sample Size ​10 mg - 30 g
    ​User Interface

    ​12 in touchscreen (30.5 cm)

    15 in touchscreen (38.1 cm)

    ​Dimensions (H x W x D) ​14.5 x 22 x 26 in (36 x 43 x 66 cm)

    ​For a full list of product specifications, see the datasheet.




    • Straightforward
      • Complete control on one screen
    • Compact
      •  Designed to take up minimal lab space
    • Flexible
      •  Configure to meet your specific needs
    • Faster
      •  New default methods speed up the flow without sacrificing performance
    • Greener
      •  Conserve solvent with optimized gradient


    Standard Features

    • Flow rates from 1 to 300 mL/min
    • Operating pressure up to 300 psi (20 bar)
    • Choice of UV, UV-Vis ELSD, or MS options
    • Customizable to meet your application needs