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ACCQPrep Verification Instruction SheetInstruction Sheet
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ACCQPrep HP125 User ManualUser Manual




ACCQPrep® HP125

Pr​ep​ar​ative liquid chromatography system

The Teledyne ISCO ACCQPrep HP125 was developed and designed with the ease of a Flash system in mind. It does not follow the traditional path of an analytical system, but rather this system has been designed to be intuitive and easy-to-use.

The ACCQPrep HP125 eliminates the unnecessary and complex integration parameters found in many of the HPLC systems in today's market. Our PeakTrak® software, which currently drives our CombiFlash® product line, is the basis for controlling the ACCQPrep HP125. By using this software, the need for a standalone PC is eliminated. This results in a smaller, more compact unit with an integrated touch screen interface.

Enjoy the confidence associated with Teledyne ISCO's active solvent and waste level monitoring which reduces the risk of solvent spills. In addition, all sample and collection racks are RFID coded eliminating the potential of missed tubes.

The ACCQPrep HP125 is compatible with Teledyne ISCO Automation Modules and other detection systems for maximum efficiency.


Standard Features

  • ​Flow rates from 1 to 125 mL/min allow development of Prep methods directly on the system without the need for pump head changes
  • Operating pressure up to 6000 psi
  • Choice of UV or UV-Vis plus ELSD and MS options


Compatible with Automation Modules

  • Use the AutoInjector Module to make multiple purification runs on the​ same sample
  • Use the AutoSampler Module if you have several different samples to purify which may require multiple injections and different chromatographic conditions
  • Use the Column Selector Module to automatically switch to the next column required for your purification

Compatible with PurIon Mass Spectrometer

  • Add mass directed fractionation to your purification
  • Use with Teledyne ISCO's PeakTrak software for single point control of all mass spectrometer parameters
  • Choose from three models to meet the needs of your application



​Flow Rate Range​1 - 125 mL/min
​Pressure Limit​up to 6000 psi (400 bar) Lower pressure limits user defined
​UV and UV-Vis Detection​​Variable UV 200 - 400 nm standard, Variable UV-Vis 200 - 800 nm option
​ELSD Detection​Integrated Option that can be combined with either UV or UV-Vis
​Number of Solvents​​Binary gradient. 2 solvent std.  2x3 solvents optional
​Programmable gradients​Linear, step, isocratic
​Gradient Linearity​+/- 1%
​Sample Introduction​Variable volume liquid load (5mL loop standard)
​User Interface​15 in touchscreen
​Fraction Collector​Internal
​Dimensions​​27.5 x 14.0 x 20.0 in (69.9 x 35.6 x 50.8 cm)
84.5 pounds (38.2 kg)
​Dimensions AS 2x1 Autosampler Module​​18.9 x 14.0 x 19.3 in (48.0 x 35.6 x 49.0 cm)​
31.1 lbs (14.1 kg)

For a full list of product specifications, see the datasheet.



When you purchase instruments from Teledyne ISCO, you not only receive innovative, high quality products, you also receive excellent customer service and product support. Your initial purchase is only the beginning of Teledyne ISCO's ongoing commitment to their customers.

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